IRCMS International Research Center for Medical Sciences

Research

Victor Appay
Eng., Ph.D.
Visiting Professor

ACHIEVEMENT

◆ Selected publications

  1. New Insights into Lymphocyte Differentiation and Aging from Telomere Length and Telomerase Activity Measurements. Fali T, Papagno L, Bayard C, Mouloud Y, Boddaert J, Sauce D, Appay V. J Immunol. 2019 Apr 1;202(7):1962-1969. doi: 10.4049/jimmunol.1801475.
  2. Phenotypic and Functional Differences between Human Herpesvirus 6- and Human Cytomegalovirus-Specific T Cells. Fastenackels S, Bayard C, Larsen M, Magnier P, Bonnafous P, Seddiki N, Appay V, Gautheret-Dejean A, Sauce D. J Virol. 2019 Jun 14;93(13). pii: e02321-18. doi: 10.1128/JVI.02321-18.
  3. HIV mediated immune aging in young adults infected perinatally or during childhood. Fastenackels S, Sauce D, Vigouroux C, Avettand-Fènoël V, Bastard JP, Fellahi S, Nailler L, Arezes E, Rouzioux C, Warszawski J, Viard JP, Appay V; ANRS Co19 COVERTE Study Group. AIDS. 2019 May 29. doi: 10.1097/QAD.0000000000002275.
  4. Priming of HIV-1-specific CD8+ T-cells with strong functional properties from naïve T-cells. Kuse N, Sun X, Akahoshi T, Lissina A, Yamamoto T, Appay V, EBioMedicine. 2019 Apr;42:109-119. doi: 10.1016/j.ebiom.2019.03.078.
  5. The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8+ T-cells. Gutjahr A, Papagno L, Nicoli F, Kanuma T, Kuse N, Cabral-Piccin M, Rochereau N, Gostick E, Lioux T, Perouzel E, Price DA, Takiguchi M, Verrier B, Yamamoto T, Paul S, Appay V. J Clin Invest Insight. 2019 Apr 4;4(7). pii: 125107. doi: 10.1172/jci.insight.125107.
  6. New insights into lymphocyte differentiation and aging from telomere length and telomerase activity measurements. Fali T, Nicoli F, Papagno L, Bayard C, Mouloud Y, Boddaert J, Sauce D, Appay V. J Immunol. 2019
  7. Naïve CD8+ T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8+ T-Cells. Nicoli F, Papagno L, Frere JJ, Cabral-Piccin MP, Clave E, Gostick E, Toubert A, Price DA, Caputo A, Appay V. Front Immunol. 2018 Dec 21;9:2736.
  8. Harnessing the Induction of CD8+ T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in  Antigen Presenting Cells. Nicoli F, Paul S, Appay V. Front Immunol. 2018 Oct 25;9:2372.
  9. Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis. Fali T, Fabre-mersseman V, Yamamoto T, Bayard C, Papagno L, Fastenackels S, Zoorob R, Koup R, Boddaert J, Sauce D and Appay V.  JCI Insight. 2018.
  10. Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses. Gutjahr A, Papagno L, Nicoli F, Lamoureux A, Vernejoul F, Lioux T, Gostick E, Price DA, Tiraby G, Perouzel E, Appay V, Verrier B, Paul S.  J Immunol. 2017 Jun 1;198(11):4205-4209.
  11. Immunological considerations regarding parental concerns on pediatric immunizations. Nicoli F, Appay V.  Vaccine. 2017 May 25;35(23):3012-3019.