IRCMS International Research Center for Medical Sciences

Research

Daisuke Kurotaki
Ph.D.
Associate Professor

PUBLICATIONS

Selected Publications

  1. Kawase W#, Kurotaki D#*, Suzuki Y, Ishihara H, Ban T, Sato GR, Ichikawa J, Yanai H, Taniguchi T, Tsukahara K, Tamura T*: Irf5 siRNA-loaded biodegradable lipid nanoparticles ameliorate concanavalin A-induced liver injury. Mol Ther Nucleic Acids, online publication ahead of print. *Corresponding authors. #Co-first authors. Web   Press Release at YCU
  2. Shibuya T, Kamiyama A, Sawada H, Kikuchi K, Maruyama M, Sawado R, Ikeda N, Asano K, Kurotaki D, Tamura T, Yoneda A, Imada K, Satoh T, Akira S, Tanaka M, Yotsumoto S: Immunoregulatory monocyte subset promotes metastasis associated with therapeutic intervention for primary tumor. Front Immunol 12: 663115, 2021. Web
  3. Murakami K, Sasaki H, Nishiyama A, Kurotaki D, Kawase W, Ban T, Nakabayashi J, Kanzaki S, Sekita Y, Nakajima H, Ozato K, Kimura T, Tamura T: A RUNX-CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes. Nat Immunol 22(3):301-311, 2021. Web
  4. Murakami K, Kurotaki D, Kawase W, Soma S, Fukuchi Y, Kunimoto H, Yoshimi R, Koide S, Oshima M, Hishiki T, Hayakawa N, Matsuura T, Oda M, Yanagisawa K, Kobayashi H, Haraguchi M, Atobe Y, Funakoshi K, Iwama A, Takubo K, Okamoto S, Tamura T, Nakajima H: OGT regulates hematopoietic stem cell maintenance via PINK1-dependent mitophagy. Cell Rep 34(1):108579, 2021. Web
  5. Kurotaki D*, Yoshida H, Tamura T: Epigenetic and transcriptional regulation of osteoclast differentiation. Bone 138:115471, 2020. *Corresponding author. Web
  6. Kurotaki D*, Kawase W, Sasaki H, Nakabayashi J, Nishiyama A, Morse HC 3rd, Ozato K, Suzuki Y, Tamura T*: Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice. Blood 133(17):1803-1813, 2019. *Corresponding authors. Web
  7. Izawa N#, Kurotaki D#, Nomura S#, Fujita T, Omata Y, Yasui T, Hirose J, Matsumoto T, Saito T, Kadono Y, Okada H, Miyamoto T, Tamura T, Aburatani H, Tanaka S: Cooperation of PU.1 with IRF8 and NFATc1 defines chromatin landscapes during RANKL-induced osteoclastogenesis. J Bone Miner Res 34(6):1143-1154, 2019. #Co-first authors. Web
  8. Kurotaki D, Nakabayashi J, Nishiyama A, Sasaki H, Kawase W, Kaneko N, Ochiai K, Igarashi K, Ozato K, Suzuki Y, Tamura T: Transcription factor IRF8 governs enhancer landscape dynamics in mononuclear phagocyte progenitors. Cell Rep 22(10):2628-2641, 2018. Web
  9. Kurotaki D, Sasaki H, Tamura T: Transcriptional control of monocyte and macrophage development. Int Immunol 29(3):97-107, 2017. Web
  10. Kurotaki D*, Tamura T*: Transcriptional and epigenetic regulation of innate immune cell development by the transcription factor, interferon regulatory factor-8. J Interferon Cytokine Res 36(7):433-41, 2016. *Corresponding authors. Web
  11. Kurotaki D, Uede T, Tamura T: Functions and development of red pulp macrophages. Microbiol Immunol 59(2):55-62, 2015. Web
  12. Sasaki H#, Kurotaki D#, Osato N, Sato H, Sasaki I, Koizumi S, Wang H, Kaneda C, Nishiyama A, Kaisho T, Aburatani H, Morse HC 3rd, Ozato K, Tamura T: Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells. Blood 125(2):358-69, 2015. #Co-first authors. Web
  13. Kurotaki D, Yamamoto M, Nishiyama A, Uno K, Ban T, Ichino M, Sasaki H, Matsunaga S, Yoshinari M, Ryo A, Nakazawa M, Ozato K, Tamura T: IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils. Nat Commun 5:4978, 2014. Web
  14. Kurotaki D, Osato N, Nishiyama A, Yamamoto M, Ban T, Sato H, Nakabayashi J, Umehara M, Miyake N, Matsumoto N, Nakazawa M, Ozato K, Tamura T: Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood 121(10):1839-49, 2013. Web
  15. Kurotaki D, Kon S, Bae K, Ito K, Matsui Y, Nakayama Y, Kanayama M, Kimura C, Narita Y, Nishimura T, Iwabuchi K, Mack M, van Rooijen N, Sakaguchi S, Uede T, Morimoto J: CSF-1-dependent red pulp macrophages regulate CD4 T cell responses. J Immunol 186(4):2229-37, 2011. Web
  16. Kanayama M#, Kurotaki D#, Morimoto J, Asano T, Matsui Y, Nakayama Y, Saito Y, Ito K, Kimura C, Iwasaki N, Suzuki K, Harada T, Li HM, Uehara J, Miyazaki T, Minami A, Kon S, Uede T: α9 integrin and its ligands constitute critical joint microenvironments for development of autoimmune arthritis. J Immunol 182(12):8015-25, 2009. #Co-first-authors. Web