Selected publications
Chin WLD, Watanabe-Okochi N, Wang CQ, Tergaonkar V, Osato M.
Mouse models for Core Binding Factor leukemia
Leukemia 29:1970-80, 2015
Koh CM, Bezzi M, Low HP, Ang WX, Teo SX, Gay FP, Al-Haddawi M, Tan SY, Osato M, Sabò A, Amati B, Wee KB, Guccione E.
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
Nature 523:96-100, 2015
Wang QC, Krishnan V, Tay LS, Chooi JY, Chin DWL, Koh CP, Chooi JY, Nah GSK, Du L, Jacob B, Yamashita N, Tan TZ, Mori S, Taniuchi I, Tergaonkar V, Ito Y, Osato M.
Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects.
Cell Reports 8:767-82, 2014
Wang QXC, Motoda L, Satake M, Ito Y, Taniuchi I, Tergaonkar V, Osato M.
Runx3 deficiency results in myeloproliferative disorder in aged mice.
Blood 122:562-66, 2013
Ng ELC, Yokomizo T, Yamashita N, Cirovic B, Jin H, Wen Z, Ito Y, Osato M.
A Runx1 intronic enhancer marks hemogenic endothelial cells and hematopoietic stem cells.
Stem Cells 28:1869-81, 2010
Taniuchi I, Osato M, Egawa T, Sunshine MJ, Bae S.C., Komori T, Ito Y and Littman DR.
Requirement for Runx proteins in CD4 silencing at different stages of T lymphocyte development.
Cell 111: 621-33, 2002