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June 11, The 5th IRCMS Seminar, "Using the avian model for understanding human diseases"

June 11 2015

We are please to invite Guojun Sheng Ph.D., Senior Investigator at Lab for Early Embryogenesis, RIKEN Center for Developmental Biology from Kobe as a speaker for our the 5th IRCMS Seminar. We encourage you to take this oppotunity to join this seminar.

Dr. Guojun will talk about their work on mesoderm formation and differentiation, and the relevance of the avian model for mechanistic understanding of human cancer and hematopoietic/vascular diseases.

Date:       Thursday, June 11, 2015, 16:00-17:00

Venue:   1F Conference Room,
               Institute of Molecular Embryology and Genetics (IMEG), Kumamoto University


16:00~16:05  Opening

Toshio Suda, Director, IRCMS


Titile: Using the avian model for understanding human diseases

Speaker: Guojun Sheng, Ph.D.


As sister amniote groups, mammals and birds share many unique features in their development. One of these features is how the mesoderm germ layer is formed. We use the avian model to study two amniote-specific processes during mesoderm formation: the epithelial-to-mesenchymal transition (EMT) process when an epithelial-shaped mesoderm precursor becomes a mesenchymal-shaped mesoderm cell, and the lineage segregation process of extraembryonic-fated mesoderm cells. I will present data from our molecular and cellular analyses of these two processes in the chick. I will also discuss their relevance to our understanding of mesoderm development in humans and of human diseases caused by mis-regulation of EMT and mesoderm lineage specification.



(Please click the image to see the full pdf flyer)

Remarks: This seminar will be held in English. Pre-registration is not required.

For futher information, please contact IRCSM office: or Tel: 096-373-6848