【Books/review/comments】Criteria for the standardization of stem-cell-based embryo models

September 17 2024

Labs: Guojun Sheng

Paper information

Title:

Criteria for the standardization of stem-cell-based embryo models

Alfonso Martinez Arias, Nicolas Rivron, Naomi Moris, Patrick Tam, Cantas Alev, Jianping Fu, Anna-Katerina Hadjantonakis, Jacob H. Hanna, Gabriella Minchiotti, Olivier Pourquie, Guojun Sheng, Liliana Solnica Krezel, Jesse V. Veenvliet & Aryeh Warmflash

Nature Cell Biology 2 Sept 2024.  doi: https://doi.org/10.1038/s41556-024-01492-x

URL: https://www.nature.com/articles/s41556-024-01492-x

Abstract:

Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.