December 7 2021
Lab: Guojun Sheng
Guojun Sheng, Alfonso Martinez Arias and Ann Sutherland
The primitive streak and cellular principles of building an amniote body through gastrulation
Science Vol 374, Issue 6572
After fertilization, a human embryo implants into the uterus (day 6-12) and gastrulation starts soon afterwards, with the primitive streak emerging at about day 14. Gastrulation allocates cell fates and spatial coordinates to epiblast cells, laying down the foundation of the human body.
Credit for the "Fetus in the womb" sketch by Leonardo Da Vinci: Royal Collection Trust / © Her Majesty Queen Elizabeth II 2021. Permission for commercial use of the "Fetus in the womb" sketch by Leonardo Da Vinci must be obtained from the Royal Collection Trust. Any non-commercial use must include the credit line.