Genetic fingerprint defines hematopoietic stem cell pool size and function.

March 9 2020

Tatsuya Morishima, Hitoshi Takizawa

Tatsuya Morishima* and Hitoshi Takizawa* (*:Corresponding authors)
Haematologica. 2020 Mar;105(3):526-528. doi: 10.3324/haematol.2019.241299.

Highlights 

An article entitled "Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance." written by Zhang et al. was published in the March issue of Haematologica.

Dr. Tatsuya Morishima and Prof. Hitoshi Takizawa reviewed this paper and were invited to write an editorial article for this paper from editorial office of Haematologica. They summarized this paper and discussed the scientific impact of the results presented in this paper.

Zhang C, Fondufe-Mittendorf YN, Wang C, et al. Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance. Haematologica. 2020;105(3):573-584.

        Cis- and trans-regulation of Lxn gene transcription modulates hematopoietic stem cell function.