What's new

News & Events

[Nov. 10] 97th IRCMS Seminar

October 30 2023

We would like to inform you that the 97th IRCMS seminar has been scheduled as below.
* This IRCMS seminar is open to everyone.

Date      : November 10, 2023 (Friday)

Time      : 16:30-17:30

ZOOM : Meeting ID: 845 2917 0099
              Passcode: ircmsSem11

Speaker : Dr. Takashi Mikawa (University of California San Francisco)

Title        :  Distance between Homologous Chromosomes

Abstract :

In meiosis, pairing of homologous chromosomes is essential for securing genetic diversity among germ cells through recombination. In somatic cells, however, close proximity between homologous chromosome could cause several problems, such as transcriptional interference as well as accidental homologous recombination leading to the loss of heterozygosity. Regulation of distance between homologous chromosomes is one of least understood processes in chromosome biology.The current dogma assumes that maternal and paternal chromosomes are randomly positions at the interphase as well as during mitosis. Our analysis of chromosome positions in human endothelial cells has suggested that maternally derived haploid set and paternally derived one are spatially segregated throughout cell cycle. Potential mechanisms for one haploid chromosome set stay together, thereby keeping homologous chromosomes apart, will be discussed.




Flyer: (Click to enlarge)

Flyer_97th IRCMS Seminar-1.jpg