IRCMS International Research Center for Medical Sciences

Research

Yasuo Ariumi
Ph.D.
Associate Professor

ACHIEVEMENT

Selected publications
  1. Ariumi Y. Multiple functions of DDX3 RNA helicase in gene regulation, tumorigenesis, and viral infection.         Front Genet. 2014;5:423.
  2. Ariumi Y, Kuroki M, Kushima Y, Osugi K, Hijikata M, Maki M, Ikeda M, Kato N. Hepatitis C virus hijacks P-body and stress granule components around lipid droplets. J Virol. 2011;85(14):6882-92.
  3. Ariumi Y, Kuroki M, Maki M, Ikeda M, Dansako H, Wakita T, Kato N. The ESCRT system is required for hepatitis C virus production. PLoS One. 2011;6(1):e14517.
  4. Ariumi Y, Kuroki M, Dansako H, Abe K, Ikeda M, Wakita T, Kato N. The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication.          J Virol. 2008;82(19):9639-46.
  5. Ariumi Y, Kuroki M, Abe K, Dansako H, Ikeda M, Wakita T, Kato N. DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication. J Virol. 2007;81(24):13922-6.
  6. Ariumi Y, Serhan F, Turelli P, Telenti A, Trono D. The integrase interactor (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription. Retrovirology. 2006;3:47.
  7. Ariumi Y, Trono D. Ataxia-telangiectasia-mutated (ATM) protein can enhance human immunodeficiency virus tyep 1 replication by stimulating Rev function. J Virol. 2006;80(5):2445-52.
  8. Ariumi Y, Turelli P, Masutani M, Trono D. DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus tyep 1 integration. J Virol. 2005;79(5):2973-8.
  9. Ariumi Y, Ego T, Kaida A, Matsumoto M, Pandolfi PP, Shimotohno K. Distinct nuclear body components, PML and SMRT, regulates the trans-acting function of HTLV-1 Tax oncoprotein. Oncogene. 2003;22(11):1611-9.
  10. Ariumi Y, Kaida A, Lin JY, Hirota M, Masui O, Yamaoka S, Taya Y, Shimotohno K. HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration. Oncogene. 2000;19(12):1491-9.
  11. Ariumi Y, Masutani M, Copeland TD, Mimori T, Sugimura T, Shimotohno K, Ueda K, Hatanaka M, Noda M. Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro. Oncogene. 1999;18(32)4616-25.
Awards: 2000. Inoue Research Award for Young Scientists
2009. Hayashibara Award
2010. Research Award from Viral Hepatitis Research Foundation of Japan