IRCMS International Research Center for Medical Sciences

Research

Shinya Suzu
Ph.D.
Professor

ACHIEVEMENT

Selected publications
  1. MPL activation directly induces fibrocyte differentiation to cause myelofibrosis. Maekawa T, Osawa Y, Izumi T, Nagao S, Takano K, Okada Y, Tachi N, Teramoto M, Kawamura T, Horiuchi T, Hikota-Saga R, Kato S, Yamamura T, Watanabe J, Kobayashi A, Kobayashi S, Sato K, Hashimoto M, Suzu S, Kimura F. Leukemia, in press
  2. Hashimoto M, Bhuyan F, Hiyoshi M, Noyori O, Nasser H, Miyazaki M, Saito T, Kondoh Y, Osada H, Kimura S, Hase K, Ohno H, Suzu S. Potential role of the formation of tunneling nanotubes in HIV-1 spread in macrophages. The Journal of Immunology 196: 1832-1841, 2016
  3. Ogawa M, Takemoto Y, Sumi S, Inoue D, Kishimoto N, Takamune N, Shoji S, Suzu S, Misumi S*. ATP generation in a host cell in early-phase infection is increased by upregulation of cytochrome c oxidase activity via the p2 peptide from human immunodeficiency virus type 1 Gag. Retrovirology 12: 97, 2015
  4. Hashimoto M, Nasser H, Bhuyan F, Kuse N, Satou Y, Harada S, Yoshimura K, Sakuragi J, Monde K, Maeda Y, Welbourn S, Strebel K, Abd El-Wahab EW, Miyazaki M, Hattori S, Chutiwitoonchai N, Hiyoshi M, Oka S, Takiguchi M*Suzu S*. Fibrocytes differ from macrophages but can be infected with HIV-1. The Journal of Immunology 195: 4341-4350, 2015
  5. Komohara Y, Morita T, Annan DA, Horlad H, Ohnishi K, Yamada S, Nakayama T, Kitada S, Suzu S, Kinoshita I, Dosaka-Akita H, Akashi K, Takeya M, Jinushi M*. The coordinated actions of TIM-3 on cancer and myeloid cells in the regulation of tumorigenicity and clinical prognosis in clear cell renal cell carcinomas. Cancer Immunology Research 9: 999-1007, 2015
  6. Osman A, Bhuyan F, Hashimoto M, Nasser H, Maekawa T, Suzu S*. M-CSF inhibits anti-HIV-1 activity of IL-32 but they enhance M2-like phenotypes of macrophages. The Journal of Immunology 192: 5083-5089, 2014
  7. Hashimoto M, Nasser H, Chihara T, Suzu S*. Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef. Cell Death and Disease 5: e1267, 2014
  8. Yamashina T, Baghdadi M, Yoneda A, Kinoshita I, Suzu S, Dosaka-Akita H, Jinushi M*. Cancer stem-like cells derived from chemoresistant tumors have a unique capacity to prime tumorigenic myeloid cells. Cancer Research 74: 2689-2709, 2014.
  9. Kariya R, Taura M, Suzu S, Kai H, Katano H, Okada S*. HIV protease inhibitor Lopinavir induces apoptosis of primary effusion lymphoma cells via suppression of NF-kB pathway. Cancer Letters 342: 52-59, 2014